Seeing the sad plight of the wretched creatures of Kaliyuga, the Supreme Lord Sri Krishna Himself, out of causeless mercy, appeared as Sri Chaitanya Mahaprabhu at Sri Mayapura, Nadia, West Bengal, India, accepting the complexion and mood of Srimati Radharani, to rescue the fallen souls.

When Lord Sri Chaitanya Mahaprabhu appeared in Sri Mayapura, West Bengal in 1486 A.D., Bengal was under the rule of a Muslim Emperor, Hussain Shah. Sri Sanatana Goswami was his Prime Minister and Sri Rupa Goswami was an important and responsible administrator. Maldah was then the capital of Bengal. Lord Sri Chaitanya Mahaprabhu first met Sri Sanatana Goswami and Sri Rupa Goswami at Ramkeli Village in Maldah District. At the first sight both were attracted by the highly impressive Divine Personality of Sri Chaitanya Mahaprabhu, who advised them to give up worldly life and join Him when He would proceed to Vrindavana. Initially, Sri Rupa Goswami and his younger brother Sri Anupam, on hearing about Mahaprabhu's departure for Vrindavana left for Vrindavana relinquishing household life. Later on, Sri Sanatana Goswami, who was imprisoned by King Hussain Shah, somehow released himself from jail and left for Vrindavana through a rural route avoiding the main thoroughfares. When he reached Benaras (Kashi), he heard about Mahaprabhu's stay at the house of Sri Chandra Shekhar Vaidya. He went there and humbly fell prostrated at the Lotus Feet of Sri Chaitanya Mahaprabhu and enquired "Who am I? Why am I being burned with threefold affliction? I do not know how I can get eternal welfare. I am not competent even to enquire about my ultimate goal of life and the means to attain it. Kindly instruct me all about the spiritual, fundamental principle."

Lord Sri Chaitanya Mahaprabhu is instructing all human beings through His personal associate Sri Sanatana Goswami that when anybody's time for getting emancipation from worldly bondage will come, he will have this theological inquiry to a bona fide guru (Divine Master). Lord Sri Chaitanya Mahaprabhu is playing the part of a guru and Sanatana Goswami of a disciple. A true disciple should search for truth and enquire into discrimination between eternal and non-eternal.

Lord Sri Chaitanya Mahaprabhu gave replies to all the above questions - Sambandha, Abhidheya and Prayojana. Sambhandha - Knowledge of God, soul and the world and their mutual relation; Abhidheya - the means; Prayojana - ultimate goal of life, real necessity of life. The subject has been dealt with elaborately in the authentic scripture "Sri Chaitanya Charitamrita" written by Sri Krishnadas Kaviraja Goswami.